Presentations of head and neck tumours including basal cell carcinoma and squamous cell carcinoma.
Nonmelanoma skin cancer represents the most common malignancy in the United States, and the incidence is increasing. In the United States alone, average annual treatment costs are in the billions. Although basal cell carcinoma (BCC) is considered the most common skin cancer, recent studies suggest the incidence of squamous cell carcinoma (SCC) has increased creating a SCC:BCC ratio of 1.0. Many treatment modalities are used for SCC including Mohs micrographic surgery, but there are currently no FDA-approved topical therapies for SCCs.
Conclusions: With appropriate patient selection and choosing as lowest dose per fraction as possible, HDR brachytherapy with customized surface molds yields good oncological and cosmetic results for the treatment of localized skin BCC and SCC.
PMID: 29789760 [PubMed]
It’s almost May and here in the northeast, front-of-the-pharmacy aisles are filled with myriad brands and types of sunscreen. While sunscreen is essential to lowering your risk for skin cancer, there are other simple, over-the-counter options you can incorporate into your summer skin protection routine.
Nicotinamide may help prevent certain skin cancers
Nicotinamide is a form of vitamin B3 that has been shown to reduce the number of skin cancers. In a randomized controlled trial performed in Australia (published in the New England Journal of Medicine), the risks of basal cell carcinoma and squamous cell carcinoma wer…
AbstractPurpose of ReviewSkin cancers, including basal cell carcinoma, cutaneous squamous cell carcinoma, and cutaneous melanoma, are the most common cancer worldwide. The treatment of these cancers is primarily surgical, and when treated early and correctly, the prognosis is excellent. In this review, we aim to discuss the appropriate surgical management of skin cancers and associated controversies as it pertains to the head and neck.Recent FindingsEvidences guiding treatment have expanded enormously over the past decade. Studies have drastically improved our understanding of skin cancer including risk factors for tumor r…
Authors: Grieco MP, Bertozzi N, Grignaffini E, Raposio E
The skin cancers of the head and neck district are localized mostly on the nose, which, by being in the center of the mid-face, has an important aesthetic role. Therefore, many reconstructive techniques have been studied; among them regional skin flaps appeared the most suitable since they guaranteed the oncological radicality as well as a good aesthetic outcome. In this paper, we present our experience with the use of the Zitelli bilobed flap, which is defined as a double transposition flap for the reconstruction of the nose defects. From 2008 to 20…
CONCLUSIONS: Skin cancer risk is increased in solid-organ transplant recipients versus the general population. Although squamous cell carcinoma is the most common tumor in this patient population, followed by basal cell carcinoma, we found this reversed in our patients. The low prevalence of skin malignancy (1.20%) may be associated with close clinical follow-up to detect premalignant skin lesions and the lowdose immunosuppressive drug regimen. We believe that local recurrence and distant metastasis were absent because we use a wide surgical margin of excision and provide strict follow-up. Routine dermatologic follow-up vi…
CONCLUSION: Orbital invasion for non-melanoma head and neck skin cancers creates a treatment dilemma and the patterns of invasion are described. In addition, the location of orbital invasion is associated with survival outcomes.
PMID: 29465316 [PubMed – as supplied by publisher]
Cutaneous malignancy of the head and neck affects a large proportion of elderly patients. The severity ranges from small, easily treatable lesions to large, invasive, potentially metastatic tumors. Surgical treatment is the primary treatment of most skin cancers; however, geriatric patients are more likely to have multiple comorbidities that increase the risk of surgery. Multiple treatment modalities exist, including surgical, radiation, and medical therapy. Recommendations and treatment options for basal cell carcinoma, squamous cell carcinoma, Merkel cell carcinoma, and melanoma are outlined and reviewed.
Radiation oncologists are increasingly tasked with the management of elderly patients with non‐melanoma skin cancer, unsuitable for surgical intervention due to inoperable lesions and/or poor performance status. In this cohort, hypofractionated radiotherapy, delivered either daily, alternative daily or once weekly is highly effective. A systematic literature search was conducted of PUBMED, MEDLINE and EMBASE databases using the algorithm (‘radiotherapy’ OR ‘radiation therapy’ OR ‘brachytherapy’) AND (‘hypofraction’ OR ‘hypofractionated’ OR ‘hypofra…
BackgroundTo assess the effectiveness and outcomes of adjuvant radiotherapy regimens for nonmelanoma skin cancers (NMSC) of the head and neck, particularly for elderly patients.
MethodsA retrospective review of patients with head and neck NMSC was conducted. Radiotherapy dose per fraction regimens included ≤200, 240–250, 300–400, and 500–600 cGy. Demographics, tumor characteristics, local control (LC), regional control (RC), and survival outcomes were analyzed.
ResultsOf the 90 patients with 140 disease sites, 76.6% were squamous cell carcinoma, 15.5% were basal cell carcinoma, and 7.7% were o…