Jade Goffin, 30, from London, thought she’d beaten a rare form of breast cancer after undergoing treatment. But she was heartbroken to find it then spread into her brain…

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Conditions:   Metastatic Breast Cancer With HER2 Positive;   Triple Negative Breast Cancer Intervention:   Procedure: Brain MRI Sponsor:   Yonsei University Not yet recruiting

Source: ClinicalTrials.govCategory: Research Source Type: clinical trials

Conclusion: The tumor control following repeat SRS for locally recurring metastatic brain tumors after a previous SRS is relatively lower than that for primary SRS. However, both low tumor volume and high prescription radiation dose were significantly related to the tumor control following repeat SRS for these tumors after previous SRS, which is a general understanding of primary SRS for metastatic brain tumors.
PMID: 30064202 [PubMed – as supplied by publisher]

Sustainable weight loss. Protection from diabetes, heart disease and cancer. Improved brain health. Enhanced physical fitness and strength. It seems like every week, researchers turn up some new and profound benefit associated with intermittent fasting: eating schedules that incorporate regular periods of low or no food consumption.
By eating normally for several days a week and eating much less on the others, a person may be able to shift her body’s cellular and metabolic processes in ways that promote optimal health. And experts who study intermittent fasting say that while many blanks still need to be filled in, s…

Source: TIME: HealthCategory: Consumer Health News Authors: Tags: Uncategorized Diet/Nutrition healthytime Source Type: news

The Breast Journal, EarlyView.

Source: The Breast JournalCategory: Cancer & Oncology Authors: Source Type: research

CONCLUSION: Our anecdotal experience suggests that eribulin may have a potentially beneficial effect on brain metastases while maintaining a good systemic control of the disease in patients with MBC.
PMID: 30041177 [PubMed – in process]

Source: OncologyCategory: Cancer & Oncology Authors: Tags: Oncology Source Type: research

It ’s difficult to open a newspaper nowadays without seeing an article about artificial intelligence. These column-inches spark our imaginations with heady visions of possible futures and crease our brows with concern in equal measure. But one thing you cannot escape is that AI is here now and it’s only going to become more pervasive.While fear of an unknown technology is understandable, in many ways it does a disservice to the incredible impact that AI is already having on the world around us. In the healthcare space alone, it is offering ways to fundamentally rethink clinical practice, speeding up diagnosis, …

Source: EyeForPharmaCategory: Pharmaceuticals Authors: Source Type: news

MiR‑500a‑5p promotes glioblastoma cell proliferation, migration and invasion by targeting chromodomain helicase DNA binding protein 5.
Mol Med Rep. 2018 Jul 09;:
Authors: Liu Z, Su D, Qi X, Ma J
Glioblastoma is one of the most common malignant primary tumors and develops in brain. The molecular mechanism that regulates glioblastoma occurrence still remains unknown. MicroRNA (miR)‑500a‑5p has been reported to be involved in hepatocellular carcinoma and breast cancer. Whether miR‑500a‑5p regulates glioblastoma progression requires further investigation. In the present study, miR‑50…

This study evaluated and compared the effects of DOX exposure from different formulations (free DOX, MMDOX and Doxil®) on the swimming activity, morphological alterations, cardiac rhythm, lethality rate and DOX biodistribution. MMDOX showed lower lethal effects, morphological alterations and neurotoxic effects than the free drug. This study shows the potential of the MMDOX to be an effective DOX-delivery system because it could reduce the side effects.
PMID: 30031011 [PubMed – as supplied by publisher]

Source: Toxicology and Applied PharmacologyCategory: Toxicology Authors: Tags: Toxicol Appl Pharmacol Source Type: research

Conclusions: WBRT remains the cornerstone of the management of brain metastases. The present study concludes that the survival of patients with brain metastases is significantly improved with female gender, good PS, primary breast cancer, time lag of>6 months between diagnosis of the primary tumor and development of brain metastases, solitary lesion, and controlled primary tumor.

Source: Indian Journal of Palliative CareCategory: Palliative Care Authors: Source Type: research

We presently forget 98% of everything we experience. That will go away in favor of perfect, controllable, configurable memory. Skills and knowledge will become commodities that can be purchased and installed. We will be able to feel exactly as we wish to feel at any given time. How we perceive the world will be mutable and subject to choice. How we think, the very fundamental basis of the mind, will also be mutable and subject to choice. We will merge with our machines, as Kurzweil puts it. The boundary between mind and computing device, between the individual and his or her tools, will blur.

Over the course of the …

Source: Fight Aging!Category: Research Authors: Tags: Newsletters Source Type: blogs

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