WebMD Medical News
By Denise Mann
Reviewed by Laura J. Martin, MD

Fewer Americans are dying from cancer.
This is one main take-away from the latest report on cancer death rates and new diagnoses of cancer in the U.S. This decline is seen among men and women across all major racial and ethnic groups, and for 17 of the most common types of cancer including lung, colon, breast, and prostate cancers.
Still, not all of the news from the new report is positive.
Rates of death are on the rise from the potentially fatal form of skin cancer, melanoma, in men; uterine cancer in women; and liver and pancreatic cancer in both sexes. What’s more, the data show a rise in cancers related to human papillomavirus (HPV) infection, and that too few at-risk people are getting the vaccine that can help prevent these cancers.
“There is substantial good news in this report,” says researcher Edgar P. Simard, PhD, MPH. He is a senior epidemiologist in the Surveillance Research Program at the American Cancer Society (ACS) in Atlanta. 
The ACS, CDC, National Cancer Institute, and the North American Association of Central Cancer Registries (NAACCR) all contributed to the new report.
Overall, cancer death rates decreased by 1.8% per year among men and by 1.4% per year among women from 2000 to 2009. Death rates among children up to 14 years of age decreased by 1.8% per year.
The reasons that fewer people are dying from cancer are likely earlier detection plus better treatments…

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Publication date: Available online 4 August 2018Source: Veterinary MicrobiologyAuthor(s): Pierrick Lucas, Eric Jouy, Laetitia Le Devendec, Claire de Boisséson, Agnès Perrin-Guyomard, Thomas Jové, Yannick Blanchard, Fabrice Touzain, Isabelle KempfAbstractResistance to extended-spectrum cephalosporins is prevalent in French pig E. coli isolates. The aim of this study was to characterize the plasmids and genes present in pathogenic and commensal extended-spectrum cephalosporins -resistant isolates. The resistance plasmids of 26 strains were sequenced and then analyzed to identify resistance and virulence …

PURPOSE OF REVIEW: Postoperative ileus (POI) is an important contributor to postoperative morbidity. However, postoperative outcomes have improved by enhanced recovery after surgery (ERAS) programs. Enteral nutrition is an essential part of ERAS and many studies suggest a therapeutic effect of nutrition on POI.
RECENT FINDINGS: Early postoperative enteral nutrition has been shown to reduce various complications, including POI, although studies are heterogeneous. Experimental studies suggest that composition and timing of the enteral feed is important for the potential beneficial effects: lipid-enrich…

Source: Clinical Colorectal CancerCategory: Cancer & Oncology Authors: Tags: Curr Opin Clin Nutr Metab Care Source Type: research

Conclusion: Delirium is a frequent condition in critically ill cancer patients admitted to the ICU. The duration in days of mechanical ventilation is potential risk factors for developing delirium during an ICU stay. Delirium was not associated with a higher rate of mortality in this group of patients.
PMID: 30073040 [PubMed – in process]

Source: Pain Research and ManagementCategory: Anesthesiology Authors: Tags: Pain Res Manag Source Type: research

Conclusions Despite a dramatic increase in the incidence of NAS in the U.S. and, in particular, the Southwest border states of AZ and NM, there is still scant research on the overall incidence of NAS, its assessment in the southwest border, and associated long-term outcomes. The Healthy Border (HB) 2020 binational initiative of the U.S.-Mexico Border Health Commission is an initiative that addresses several public health priorities that not only include chronic and degenerative diseases, infectious diseases, injury prevention, maternal and child health but also mental health and addiction. The growing opioid epidemic and r…

Authors: Wang X, Yang YE, Jia L, Chen Q
PMID: 30073155 [PubMed – in process]

Conclusion: The tumor control following repeat SRS for locally recurring metastatic brain tumors after a previous SRS is relatively lower than that for primary SRS. However, both low tumor volume and high prescription radiation dose were significantly related to the tumor control following repeat SRS for these tumors after previous SRS, which is a general understanding of primary SRS for metastatic brain tumors.
PMID: 30064202 [PubMed – as supplied by publisher]

Authors: Jia L, Guo H, Liu M, Gao Y, Zhang L, Li H, Xie S, Zhang N
Background: We aimed to construct an adenovirus expressing a cross-reactive fragment of the apical membrane antigen 1 (AMA1) antigen and evaluated the concomitant immune response in BABL/c mice, allowing protection against N. caninum and T. gondii infection.
Methods: The study was conducted in Agricultural College of Yanbian University, Yanji, Jilin, China In 2015-2016. Primers were designed using the AMA1 gene sequences of N. caninum (AB265823.1) and T. gondii (AF010264.1). After linearization of the plasmid ADV4-NcAMA1 and the framewo…

Conclusion: USM.TOXO1 is a potential vaccine candidate that elicits strong immunity in BALB/c mice. The proven immunogenicity of the generated antigen can serve as a premise for further use of epitope-based vaccine in the immunoprevention of human and animal toxoplasmosis.
PMID: 30069205 [PubMed]

Conclusion: p27 gene and protein can be considered as a target in recombinant vaccine production and treatment process.
PMID: 30069202 [PubMed]

MicroRNA‑106a regulates the proliferation and invasion of human osteosarcoma cells by targeting VNN2.
Oncol Rep. 2018 Jul 26;:
Authors: Chen Y, Huang T, Yang X, Liu C, Li P, Wang Z, Zhi S
MicroRNAs (miRs) serve an essential role in tumorigenesis and are able to act as tumor suppressor genes or oncogenes. miR‑106a has been identified generally as an oncogene in multiple types of human cancer; however, its association with osteosarcoma has not previously been understood. Reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR) was used to detect miR‑106a expression in 18 …

Source: Oncology ReportsCategory: Cancer & Oncology Tags: Oncol Rep Source Type: research

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