Researchers from the Barcelona Institute for Global Health believe health bodies erred on the side of caution when they declared such radiation as possibly cancer causing in 2011.

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BOSTON (CBS) – Researchers in Europe find that both teetotalers and those who drink more heavily during middle age are at higher risk of dementia as they get older.
Researchers looked at 9,000 adults in the United Kingdom and found that people who abstained from alcohol were more likely to develop dementia as well as those who drank more than 14 glasses of wine a week. The more alcohol they drank, the higher the risk. And for those with an alcohol disorder, the risk of dementia doubled.
Researchers say drinking on one to eight drinks a week may benefit brain health but there are downsides to regular alcohol use like …

AbstractBackgroundTo assess the impact of location versus number of extra-pulmonary metastatic sites (EPMS) on survival in stage IV non-small cell lung cancer (NSCLC).Methods and materialsRetrospective analysis was conducted on patients diagnosed during 1999 –2013 with stage IV, M1b (AJCC 7th edition) NSCLC using the large, institutional Glans-Look Database, which contains patient demographic, clinical, pathological, treatment, and outcome information. We assessed the impact of location and number of EPMS and identified correlates of overall survival using the Kaplan–Meier method and Cox regression.ResultsWe id…

Source: Medical OncologyCategory: Cancer & Oncology Source Type: research

ConclusionsAtezolizumab was safe and well tolerated in this group of patients with recurrent glioblastoma. Our preliminary findings suggest that biomarkers, including peripheral CD4+  T cells and hypermutated tumor status, may help guide selection of patients with recurrent glioblastoma who might receive most benefit from atezolizumab therapy, supporting further atezolizumab combination studies in glioblastoma.

To drink or not to drink when it comes to your health really depends on a few important factors, including how much you imbibe and what health issues you’re concerned about. Alcohol in moderation can lower the risk of heart disease for some people, as well as reduce the risk of type 2 diabetes and gallstones. But excessive drinking — more than about a drink a day for women and two drinks a day for men — is also linked to several types of cancer, including breast, colon, pharynx, larynx and esophageal. Too much alcohol can also take a toll on the liver.

Some studies have also suggested that moderate drink…

Source: TIME: HealthCategory: Consumer Health News Authors: Tags: Uncategorized Alcohol Brain Dementia Source Type: news

Doug Ethell has a clear and comparatively easily tested hypothesis on an important cause of Alzheimer’s disease: that it results from the progressive failure of drainage of cerebrospinal fluid through one particularly crucial pathway in the skull. This traps ever greater levels of metabolic waste in the brain, such as amyloid-β, tau, and α-synuclein, and leads to the spectrum of well-known neurodegenerative diseases characterized by protein aggregates and resultant dysfunction and death of neurons.

Dave Gobel of the Methuselah Foundation backed the first work on this hypothesis a few years back, and the r…

Source: Fight Aging!Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs

Sustainable weight loss. Protection from diabetes, heart disease and cancer. Improved brain health. Enhanced physical fitness and strength. It seems like every week, researchers turn up some new and profound benefit associated with intermittent fasting: eating schedules that incorporate regular periods of low or no food consumption.
By eating normally for several days a week and eating much less on the others, a person may be able to shift her body’s cellular and metabolic processes in ways that promote optimal health. And experts who study intermittent fasting say that while many blanks still need to be filled in, s…

Source: TIME: HealthCategory: Consumer Health News Authors: Tags: Uncategorized Diet/Nutrition healthytime Source Type: news

(The Korea Advanced Institute of Science and Technology (KAIST)) A new study by KAIST researchers identified where the mutation causing glioblastoma starts. According to the study, neural stem cells away from the tumor mass are the cells of origin that contain mutation drivers for glioblastoma, one of the most aggressive brain tumor. This breakthrough research, reported in Nature on August 1, 2018, gives insights for understanding why glioblastomas almost always grow back, even after surgery, and suggests novel ways to treat glioblastoma, which was previously thought to be incurable.

SummaryThe administration of target inhibitors is paramount to grant the longest survival in patients with ALK-positive non-small cell lung cancer (NSCLC). The eventual resistance to tyrosine kinase inhibitors (TKI) is monitored clinically and radiologically for prompt molecule shift to further generation TKI, if available. However, the early radiological detection of progression pattern (e.g. nodule onset) should be regarded with caution because overlaps exist with non-tumor cell proliferation and/or accumulation. Here we report the case of a stage IVALK-rearranged NSCLC patient exposed to serial crizotinib, brigatinib, c…

Glioblastoma is the most common and aggressive brain tumor, with a subpopulation of stem-like cells thought to mediate its recurring behavior and therapeutic resistance. The epithelial–mesenchymal transition (EMT) inducing factor Zeb1 was linked to tumor initiation, invasion, and resistance to therapy in glioblastoma, but how Zeb1 functions at molecular level and what genes it regulates remain poorly understood. Contrary to the common view that EMT factors act as transcriptional repressors, here we show that genome-wide binding of Zeb1 associates with both activation and repression of gene expression in glioblastoma …

Source: EMBO JournalCategory: Molecular Biology Authors: Tags: Cancer, Signal Transduction, Transcription Articles Source Type: research

(Natural News) Roughly sixty percent of all brain cancer are gliomas, a tumor that starts in the glial cells of the brain or the spine. There are many different grades of gliomas; each describing a variance in growth potential and aggressiveness. Regardless, conventional therapies involving radiation and chemotherapy drugs have been shown to be inconsistent…

Source: NaturalNews.comCategory: Consumer Health News Source Type: news

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