Some 200 students in the Class of 2016 will receive their medical degrees June 3 during the Hippocratic Oath Ceremony for the David Geffen School of Medicine at UCLA. Earning an M.D. requires grueling hours, demanding classes and unwavering focus. The following students hurdled enormous obstacles to achieve that goal, making their accomplishments all the more remarkable.
Teen mother overcomes lifetime of abuse to achieve M.D.
Rebecca Lopez, 37, from Covina in the San Gabriel Valley, survived childhood abuse, became a mother at age 14 and endured a violent marriage, but never surrendered her dream of becoming a doctor. At 27, she returned to college at UCLA and was chosen for a prestigious Albert Schweitzer Fellowship in medical school. Her project helped pregnant girls in East Los Angeles prepare for motherhood, and drew heavily on her experience as a teen parent and survivor of domestic violence. After completing a residency in family medicine, Lopez said her goal is to inspire teen girls to follow their dreams, no matter the obstacles. Her daughters, ages 13, 18 and 22, have taken her message to heart. Her middle child, Emiko, graduates high school three days later. She will continue her education at UC Riverside and plans to become a physician, just like her mom.
Farmworkers’ daughter encourages immigrant kids to pursue medical career
Luz Corona Gomez, 30, from Fresno, was born to migrant farmworkers and helped her parents pick grapes as a child d…

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Publication date: Available online 9 August 2018Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Katrine Togsverd-Bo, Peter Alshede Philipsen, Merete Haedersdal, Hans Christian WulfAbstractBackgroundSkin autofluorescence and pigmentation can estimate photodamage and sun exposure. These techniques may quantify differences in actinic damage between high-risk organ transplant recipients (OTRs) and immunocompetent patients.MethodsAge and gender-matched OTRs (n = 15) and immunocompetent controls (n = 15) with a new keratinocyte carcinoma (KC) were included. We measured skin autofluorescence (370…

ConclusionEvolution and prognosis evaluation remain hard and could necessitate a radical surgery. Prognosis criteria for the bladder PEComas have to be clarified.

Publication date: Available online 9 August 2018Source: Actas Urológicas Españolas (English Edition)Author(s): J.A. March-Villalba, J. Panach-Navarrete, M.J. Herrero-Cervera, S. Aliño-Pellicer, J.M. Martínez-JabaloyasAbstractIntroductionTo study the relationship between quantitative mRNA determination (hTERT) in patients with bladder tumor, history of bladder tumor, and in subjects without a history of this neoplasia.Material and methodsA prospective randomized controlled study with 91 subjects included. The value of mRNA-hTERTN was determined in 63 patients with a history or suspicion of bladde…

Publication date: Available online 9 August 2018Source: Actas Urológicas Españolas (English Edition)Author(s): F. Gómez-Veiga, A. Alcaraz-Asensio, J. Burgos-Revilla, J. Cózar-OlmoAbstractObjectiveTo put forth new findings of urologic oncology with an impact on clinical practice presented during 2017 in the main annual meetings.MethodsThis document reviews abstracts on prostate, kidney and bladder cancer presented at the congresses of 2016 (EAU, AUA, ASCO, ESMO and ASTRO) and publications with the highest impact in this period valued with the highest scores by the OncoForum committee.ResultsAmong…

A breast cancer survivor who ran one of the most notorious brands in fashion is now C.E.O. of Susan G. Komen, working to raise money for a cure.

Source: NYT HealthCategory: Consumer Health News Authors: Tags: Breast Cancer Fashion and Apparel American Apparel Inc Komen, Susan G, for the Cure Schneider, Paula Charney, Dov Source Type: news

ConclusionEmergency surgical treatment of abdominal metastases of a lung cancer is mandatory but prognosis is extremely unfavorable.

ConclusionFine needle aspiration cytology should be done in cutaneous nodules associated with head and neck cancers to rule out malignancy, even if it clinically appears to be benign in nature.

This study does have limitations. For one, it relied on women to accurately remember what they ate in the past, and didn’t prove that the dietary differences actually caused the shifts in menopausal age.
In addition, it included only 900 women — the ones who began menopause — in its final analysis, and used a relatively short four-year follow-up period, says Dr. Ley. That said, the findings are still worth noting, she says. They add to the ongoing discussion about the role of diet in menopause. They also seem to back up data from the Nurses’ Health Study II, which suggested that dietary factors &mda…

Source: Harvard Health BlogCategory: Consumer Health News Authors: Tags: Health Healthy Eating Menopause Vaccines Source Type: blogs

We examined the use of DNA methylation profiles to determine the efficacy of anti-PD-1 treatment in patients recruited with current stage IV NSCLC.MethodsIn this multicentre study, we recruited adult patients from 15 hospitals in France, Spain, and Italy who had histologically proven stage IV NSCLC and had been exposed to PD-1 blockade during the course of the disease. The study structure comprised a discovery cohort to assess the correlation between epigenetic features and clinical benefit with PD-1 blockade and two validation cohorts to assess the validity of our assumptions. We first established an epigenomic profile ba…

We describe 2 patients with unicentric Castleman disease complicated by paraneoplastic pemphigus and bronchiolitis obliterans. In addition to primary surgical resection for Castleman disease, we also used therapy from a treatment protocol used for bronchiolitis obliterans resulting from hematopoetic stem cell transplant (HSCT). We were able to treat the patients using intravenous immunoglobulin; rituximab; fluticasone, azithromycin, and monteleukast (FAM); and rosuvastatin therapy. One patient demonstrated a favorable response, while the other demonstrated minimal response to this therapy.

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