Zollinger-Ellison syndrome is a complex condition in which tumor formation in the pancreas or in the duodenum causes excessive production of hydrochloric acid in the stomach, leading to peptic ulcers. Common symptoms include heart burn, burning and pain in the stomach, nausea, vomiting, loose motions, bleeding in the stools and weight loss.
The Ayurvedic treatment of Zollinger-Ellison syndrome is aimed at treating the symptoms of peptic ulcers and also treating the pancreatic or duodenal tumors. Medicines like Shankh-Bhasma, Praval-Bhasma, Praval-Panchamrut-Bhasma, Sutshekhar-Ras, Bhunimbadi-Qadha, Kamdudha-Ras, Laghu-Sutshekhar-Ras and Swadishta-Virechan-Churna can be used to treat the excessive acid production and peptic ulcers. Herbal medicines which can be used for this purpose are: Amalaki (Emblica officinalis), Haritaki (Terminalia chebula), Behada (Terminalia bellerica), Sunthi (Zinziber officinalis), Kalmegh (Andrographis paniculata), Bhrungraj (Eclipta alba), Yashtimadhuk (Glycerrhiza glabra), Saariva (Hemidesmus indicus), Usheer (Vetiveria zizanioidis), Chandan (Santalum album), Guduchi (Tinospora cordifolia), Ashwagandha (Withania somnifera) and Shatavari (Asparagus racemosus). Diarrhea can be treated using medicines like Laghu-Sutshekhar-Ras, Kutaj-Parpati, Kutaj (Holarrhina antidysentrica) and Musta (Cyperus rotundus). Bleeding from the peptic ulcers can be treated using medicines like Haridra (Curcuma longa), Yashtimadhuk, Vasa (Adhatoda vasaka), Naagkeshar (Messua ferrea) and Sphatik-Bhasma. Stress can be treated using medicines like Brahmi (Bacopa monnieri), Jatamansi (Nardostachys jatamansi), Khurasani ova (Hyoscyamus niger) and Sarpagandha (Rauwolfia serpentina).
Tumors in the pancreas or duodenum can be treated using medicines like Kaishor-Guggulu, Triphala-Guggulu, Kanchnaar-Guggulu, Maha-Manjishtadi-Qadha, Saarivadi-Churna, Amalaki, Haritaki, Punarnava (Boerhaavia diffusa), Nimba (Azadirachta indica), Patol (Tricosanthe dioica), Patha (Cissampelos pareira), Chirayta (Swertia chirata), Mandukparni (Centella asiatica), Varun (Crataeva nurvala), Suvarna-Sutshekhar-Ras, Panchamrut-Parpati, Suvarna-Parpati, Trivang-Bhasma, Tamra-Bhasma and Heerak-Bhasma.
It is important to make an early diagnosis of Zollinger-Ellison syndrome and to initiate treatment at the earliest, in order to prevent local complications and the spread of the tumor to other parts of the body. Ayurvedic medicines can be given in addition to modern medicine to improve the therapeutic response, prevent long term complications and improve the survival rate. People suffering from symptoms of hyperacidity should avoid prolonged self-treatment, since this may mask the symptoms and delay the diagnosis of this condition.